What are Senescent cells and why are doctors and researchers getting excited over it?
If you are not in the medical or research field then chances are that you have not yet heard of the term senescent cells. This article was researched and created to give a basic and informative guide to stem cell therapy and how it is revolutionizing the fight against aging.
It is an exciting time to be alive right now in this era, there are now different types of available technology that can be used by man to improve their quality of life. One of the latest improvements in the fight against aging is the discovery of Senescent Cells.
What are Senescent cells?
The first encounter of senescent cells occurred in the 1960’s, but it was only in 2010 when breakthrough discoveries were made in the name of science. Senescent cells are one of the many causes why humans start aging. As we grow older, there is an increase in the number of cells that start to enter the stage of senescence. These cells no longer divide or support the tissue where they are located, and they begin to release harmful chemical signals that cause inflammation that speeds up the process of aging.
However, not all senescent cells are bad, they serve a function inside the body. These cells are needed to provide safety measures for cells to prevent the spread of damaged cells or cell death. Senescence is one way to keep us from suffering from cancer and promote healthy tissue repair. It only starts becoming trouble when there is too much of it inside the body.
Why are doctors and scientists excited?
Scientists and researchers cannot contain their excitement, in truth even elderly mouse should be excited to live in the present time if they have mental awareness. In current research findings conducted researchers now believe that by removing senescent cells, cells that have already damaged response they can slow down the process of aging.
In an experiment conducted with adult mice, the tests have shown that senior rodents can regrow hair, run faster and improve organ function after the decrease of senescent cells inside their body. This breakthrough strategy is now considered as another step closer to the ” Fountain of Youth”.
Senescence Therapy
The removal of the senescent cells is now considered as a therapeutic option to combat the aspects of aging. it is likened to getting a replacement of broken parts when you are undergoing car repair. According to de Keizer, one of the leading experts in this study ” “A perfect anti-senescence therapy would not only clear senescent cells but also kick-start tissue rejuvenation by stimulating differentiation of nearby stem cells. This may be complementary with, for instance, the exciting approaches recently made in the field of transient expression of stem cell factors ( (Cell, 10.1016/j.cell.2016.11.052).
Anti-Senescence Approach
- Taking out senescent cells inside the body of aging mice allowed the test subject to live 25% live longer than those who did not undergo the procedure.
- Safe Therapeutics and Anti-senescent drugs are already being tested and undergoing tests with the goal of improving its ability to fight aging.
New Study to make Senolytic Drugs Safer to use
Admittedly, there are still a lot of things that need to be studied together with this new discovery. The good news is that researchers have come out with a new study or approach when it comes to senescent cells. The new approach with the use of senolytic drugs has fewer side effects, this means that during the extraction of removal of the senescent cells there are lesser healthy cells that would be affected. It means that the drug can be delivered system-wide and it will only damage the senescent cells causing aging. it works by directly targeting the problem deeming the therapy more effective than ever.
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About the Author:
Kali Alaia is a digital marketer, strategist, researcher, and content provider. The articles posted on this site is based on a number of medical journals and sources found online and are intended for educational purposes only. Any recommendations in here are not intended to replace the recommendation of your doctor. Always seek your attending physician before submitting to any suggestions posted on this website. The personal stories and content are curated as a way to inform.